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How to Apply Transdermal Medications to Animals

This is a guide for caring animal owners detailing how to administer transdermal medications to canine, feline or other pet or animal friends. 

How Topical Veterinary Medications Work

My veterinarian has suggested I use a transdermal medication for my pet. What is it?

Transdermal means the application of a medicine or drug through the skin. In the simplest terms, a drug is placed on top of the skin, where it is absorbed into the bloodstream.

Transdermal medications have many advantages, chief among them ease of application. Medications that can be absorbed through the skin bypass the need for pills or liquids, which can be a challenge to administer to some pets. In addition, because they are absorbed directly into the bloodstream and avoid initially passing through the intestinal and liver, drugs that are administered transdermally may be more effective or work faster than some oral medications, allowing for better treatments.

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How Do I Administer a Transdermal Medication to My Pet?

The ideal application site for transdermal medications is one that has minimal hair and that cannot be easily licked or rubbed. Some pets may require shaving to allow for better administration. The inside of the outer ear flap (not inside the ear canal) is an excellent area for many pets.
Most transdermal medications will come in pre-dosed syringes or in gel form that you can draw into a syringe to the prescribed dosage. You should wear protective gloves when handling transdermal medications. Remember that these drugs have been formulated to cross the skin barrier, and you can potentially be exposed if you come in contact with them.

To avoid being exposed to the drug, wear protective gloves when handling transdermal medications. If your pet is prescribed a transdermal gel, you may need someone to assist you, especially at first.

Here are Some Tips for Administration:

• Have your helper gently hold your pet and distract it by petting or offering a toy or treat.

• Make sure the area on the ear where you are going to apply the medication is clean and dry.

• Slowly and deliberately apply (“squirt”) the correct amount of medication onto your pet’s ear.

• If necessary, gently rub the gel into the skin to facilitate absorption using your gloved fingertip or the tip of the syringe. It is important not to leave a clump, glob, or thick area of medication on the ear because it will be easily dislodged if your pet shakes its head after administration.

After you’ve administered the medication, try to distract your pet from scratching or rubbing the ear for a few minutes. This can best be accomplished by feeding your pet, taking your pet for a walk, or playing together immediately afterward. Such a reward also functions as an excellent training technique that can help teach your pet not to fear the application of medications.

If your pet is prescribed a transdermal medication patch, your veterinarian will often shave an area to affix the patch. Many patches will last for several days, and the patch may have a protective wrap or bandage over it. Your veterinarian will explain the proper care, duration, and monitoring of transdermal patches. It is very important that your pet not be allowed to lick or swallow the patch. Serious side effects may result if a pet inadvertently consumes a patch, especially one containing fentanyl, a pain-relief drug.

Serious side effects may result if a pet consumes a transdermal patch.

Ask your veterinarian if you have any questions or concerns about your pet’s transdermal medication.

What is the Key Takeaway Message?

Transdermal medications are an excellent alternative for some veterinary drugs, and our options are increasing each year. Talk to your veterinarian to determine if a transdermal medication is appropriate for your pet.

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